The risk of an abdominal aortic aneurysm (AAA), a life-threatening condition is increased by a number of factors, such as older age, male sex, hypertension, smoking, and coronary heart disease. The pathophysiology of an AAA is complex, and some studies emphasize the degradation of connective tissues, genetic determinants, inflammation, as well as oxidative stress. However, maintaining the homeostasis of certain macroelements and microelements may decrease chronic inflammation and oxidative stress. The aim of the present study was to evaluate the effects of pre- and postoperative treatment on the levels of calcium (Ca), magnesium (Mg) and iron (Fe) in AAA patients qualified for surgery. The study involved 40 AAA patients, divided into two groups based on interviews and clinical examination: a high-surgical-risk (EVAR) group included 20 patients, whereas a low-surgical-risk (OR) group comprised 20 patients. Mg, Ca and Fe levels were measured using colorimetric assay kits. The concentrations of Ca, Mg and Fe did not differ between the OR and EVAR groups prior to surgery. Postoperatively, the tendency to decrease in Mg levels were observed in the OR group (1 day after surgery: 2.11±0.36 mg dl-1; 2-4 days after surgery: 1.81±0.56 mg dl-1). Moreover, the OR group demonstrated significantly lower Mg levels in comparison to EVAR 2-4 days after surgery, and Fe levels were considerably lower both in the OR and EVAR groups postoperatively, as compared to the values observed before surgery. According to the obtained results, AAA development did not affect blood levels of Ca, Mg and Fe. However, OR procedures contributed to a decrease in Mg levels during the postoperative period and postoperative treatment reduced plasma concentration of Fe, regardless of the type of surgery.