Otrzymano: Luty 24, 2021
Zaakceptowano: Październik 22, 2021
Opublikowano online: 2021-10-29
Medicine and veterinary
Gut microbiota is involved in the metabolism of calcium, iron, magnesium, selenium, copper, zinc, and silver. Previous research indicates that the mineral status of an organism is associated mostly with the mineral content in the diet, but there is also evidence for probiotic bacteria having an effect on facilitating mineral absorption. However, the effect of probiotic supplementation on the gut microbiota composition is not clear, with some studies pointing towards no effect, or towards individual and strain-specific efficacy. Hair samples were previously established as a biomarker of dietary mineral intake over the previous 6-8 weeks. The aim of this research was to test the hypothesis that prophylactic consumption of Bifidobacterium lactis BS01 and Lactobacillus acidophilus LA02 can impact the mineral status in healthy females. The study utilizes a randomized, single-blind, placebo-control design. 53 healthy females between 19 and 33 years old were enrolled, and 38 completed the trial. A 6-week supplementation with Bifidobacterium lactis BS01 and Lactobacillus acidophilus LA02 or placebo was conducted. Participants were asked not to change any of their diet and lifestyle habits during the study. The contents of Ca, Mg, Zn, Cu, and Fe in hair samples were determined by flame atomic absorption spectrometry. The outcome of this study provides evidence that Bifidobacterium lactis BS01 and Lactobacillus acidophilus LA02 strains might be useful for improving the mineral status in healthy people (without dietary intervention), increasing Ca, Mg, Fe, and decreasing Cu concentration in hair, changing the mineral balance. The results support the hypothesis that probiotics might possibly have antidepressant properties.
Czajeczny D., Kabzińska-Milewska K., Wójciak R.W. 2021. Bifidobacterium lactis BS01 and Lactobacillus acidophilus LA02 supplementation may change the mineral balance in healthy young women. J. Elem., 26(4): 849 - 859. DOI: 10.5601/jelem.2021.26.1.2121
hair, minerals, probiotics, supplementation, women