Relationship of magnesium level with glycemic control and lipid profile in adult patients with type 1 diabetes mellitus
Issue: 2/2021
Recevied: Jan 05, 2021
Accepted: Apr 06, 2021
Published: June 6, 2021
Authors:
Andac B., Yilmaz Bulbul B., Durak D., Celik M.
Categories: Medicine and veterinary
DOI: 10.5601/jelem.2021.26.1.2096
Abstract:
Type 1 diabetes mellitus (T1 DM) is a disease caused by the autoimmune destruction of pancreatic beta cells due to environmental factors in individuals with genetic predisposition. Magnesium (Mg) is one of the environmental factors suggested to be effective in the pathogenesis and progression of T1 DM. While studies link Mg deficiency with poor glycemic control and dyslipidemia, there are also findings suggesting no association. We aimed to assess the serum Mg levels in adults with T1 DM and evaluate its relationship with glycemic control and lipid profile. The study included 95 type 1 diabetic patients, who presented at the Endocrinology outpatient clinic, and 95 age- and gender-matched individuals without chronic disease. The comparison between the study groups was made using Student's t-test for qualitative data analysis and Mann-Whitney U test for quantitative data analysis without normal distribution. The Mg level of the diabetic patients was significantly lower than in the control group (p
Citation:
Andac B., Bulbul B.Y., Durak D.M., Celik M. 2021. Relationship of magnesium level with glycemic control and lipid profile in adult patients with type 1 diabetes mellitus. J. Elem., 26(2): 307-317. DOI: 10.5601/jelem.2021.26.1.2096
Keywords:
type 1 diabetes mellitus, adults, magnesium, lipid profile
About issue:
26.2.2021
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