Skip to content
Journal Title Abbrev.
J. Elem.
ISSN – 1644-2296
DOI: 10.5601

Search article

Language
flag flag
Selenium in medicine and treatment

Issue: 1/2013

Recevied: No data

Accepted: Brak danych

Published: March 29, 2013

Authors:

Brak danych

Categories: Medicine and veterinary, Review paper

DOI: 10.5601/jelem.2013.18.1.13

Abstract:

Selenium, one of non-metals, has attracted great interest among many researchers over the last years. Properties of selenium were first mentioned back in the 12th century. Selenium exists in two forms, organic and inorganic one. But whatever the form of supplementation, it is an essential micronutrient conditioning many vital functions. Large-scale research has shown that it has many important properties, including antioxidant ones, for living organisms. It is incorporated in many enzymes and proteins. Numerous studies on this element have demonstrated its beneficial effects, mainly on the cardiovascular and nervous systems. It also contributes to reduction in the incidence of many neoplastic diseases. However, despite numerous desirable effects of this element in the human body, it should be remembered that selenium is also a toxic substance with a narrow therapeutic index. Its excessive consumption contributes to the development of a condition called selenosis. The recommended dose of selenium, depending on the patient’s age, ranges from 25 to 70 μg 24 h–1. However, selenium in excess of 700 μg 24 h–1 shows strong toxicity. Therefore, adequate selenium supplementation is crucial. Nonetheless, despite numerous studies on selenium and its biological role, this trace element still raises many unresolved questions.

Citation:

quote-mark
Frączek A., Pasternak K. 2013. Selenium in medicine and treatment. J. Elem. 18(1): 145-163, DOI: 10.5601/jelem.2013.18.1.13.

Keywords:

selenium, qualities of selenium, selenium deficiency, excess of selenium

About issue:

18.1.2013
Download article
Jsite