Urine iodine excretion in patients with papillary thyroid cancer evaluation of the relationship with the presence of BRAF mutation
Issue: 3/2020
Recevied: Mar 06, 2020
Accepted: May 16, 2020
Published: July 17, 2020
Authors:
Celik M., Guldiken S., Ayturk S., Yilmaz Bulbul B., Kucukarda A., Can N., Tastekin E., Sezer A., Sut N., Tugrul A., Gurkan H., Tozkir H., Demirkan B.
Categories: Biology and microbiology, Food science, Medicine and veterinary
DOI: 10.5601/jelem.2020.25.1.1984
Abstract:
Iodine is an essential element for the production of thyroid hormones. In recent years, it has been suggested that excessive consumption of iodine may play a role in the pathogenesis of papillary thyroid cancer (PTC). In addition, studies have suggested that high iodine consumption is an important risk factor for the formation of a BRAF mutation in the thyroid gland. A prospectively designed study included 132 cases scheduled for thyroidectomy for various reasons. Urine iodine levels of all patients were examined before the operation. The iodine excretion levels of the patients were grouped according to the median urinary iodine concentration determined in community screenings (those with
Citation:
Celik M., Guldiken S., Salt S.A., Bulbul B.Y., Kucukarda A., Can N., Tastekin E., Sezer A., Sut N., Tugrul A., Gurkan H., Tozkir H., Demirkan B. 2020. Urine iodine excretion in patients with papillary thyroid cancer evaluation of the relationship with the presence of BRAF mutation. J. Elem., 25(3): 1019 - 1028. DOI: 10.5601/jelem.2020.25.1.1984
Keywords:
papillary thyroid cancer, BRAF mutation, urine iodine excretion
About issue:
25.3.2020
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