Relationship between chronic complications of type 2 diabetes mellitus and hypomagnesemia
Grudzień 31, 2019
Luty 09, 2020
Akyüz O., Ardahanlı I., Aslan R.
Chronic complications of diabetes are an important cause of morbidity, mortality and health costs worldwide. Magnesium is involved in many important physiological processes in the body. We aimed to investigate the relationship between hypomagnesemia levels and metabolic values and chronic complications of diabetes in type 2 diabetes mellitus in patients. 103 patients with type 2 diabetes mellitus but without any conditions affecting serum magnesium levels were included in the study. Patients were divided into two groups (normal and low blood magnesium levels). Chronic complications of type 2 diabetes mellitus were evaluated by measuring HbA1C, HDL-cholesterol, LDL-cholesterol, triglyceride and magnesium levels. Magnesium was found to be significantly lower in patients with type 2 diabetes mellitus and neuropathy (n=10, p=0.040). There was an inverse correlation between HbA1c and magnesium. However, there is no significant relationship between magnesium levels and HDL-cholesterol, LDL-cholesterol, triglyceride. Hypomagnesemia was associated with poor glycemic control. Hypomagnesemia seen in diabetic patients should be kept in mind as it may be related to neuropathy and hypertension itself or its course. In the course of diabetes mellitus, we recommend that serum magnesium levels be monitored at regular intervals and magnesium replacement be administered in patients who develop complications.
Akyüz O., Ardahanlı I., Aslan R. 2020. Relationship between chronic complications of type 2 diabetes mellitus and hypomagnesemia. J. Elem., 25(2): 565 - 579. DOI: 10.5601/jelem.2020.25.1.1951
Type 2 Diabetes Mellitus, Hypomagnesemia, Chronic complications of diabetes